Newsletter: March 2015

Newsletter of March 2015

9th vaccine congress

Spotlight on ISV Fellows - Dr. Ray Spier

Dr Ray Spier International Society for Vaccine Fellow: Elected 2013, Raymond E. Spier, DPhil- Emeritus Professor of the University of Surrey, UK

Having been educated at Christ Church, Oxford and University College, London in Biochemistry (First Class Honours), Chemical Microbiology and Biochemical Engineering he then spent 7 years as a Senior Process Engineer in industry. The last 3 years in America were spent with Merck Sharpe and Dohme where he was introduced to animal cell biotechnology and the production of viruses for use in veterinary and human vaccines. On returning to the UK he worked for 10 years at the Animal Virus Research Institute, Pirbright, scaling-up bioreactors for virus vaccine production processes and maximizing the biological productivity of the BHK cell lines for Foot-and-Mouth Disease virus generation. He then moved to the University of Surrey as Professor and was Head of Microbiology (7 years) and was then (1997) appointed to the first chair in the UK in ‘Science and Engineering Ethics’. His publication record includes ...read more

Paper of the Month 2015

  • Paper of the Month Feb 2015


    Tapping the Potential of DNA Delivery with Electroporation for Cancer Immunotherapy

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  • Paper of the Month Jan 2015


    The Combination of ISCOMATRIX Adjuvant and TLR Agonists Induces Regression of Established Solid Tumors In Vivo.

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  • Paper of the Month Nov 2014


    Chimpanzee Adenovirus Vector Ebola Vaccine - Preliminary Report.

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  • Paper of the Month Oct 2014


    Prime-Boost Immunization Strategies against Chikungunya Virus.

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  • Paper of the Month September 2014


    TLR5-Mediated Sensing of Gut Microbiota Is Necessary for Antibody Responses to Seasonal InfluenzaVaccination.

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  • Paper of the Month August 2014


    Efficacy of high-dose versus standard-dose influenza vaccine in older adults.

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  • Paper of the Month July 2014


    Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial.

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  • Paper of the Month June 2014


    Early development of broadly neutralizing antibodies in HIV-1–infected infants

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  • Paper of the Month May 2014


    Analysis of HLAA*02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial.

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    4th Computational Vaccinology Workshop at ISV
  • Paper of the Month April 2014


    Economic Evaluation of the Routine Childhood Immunization Program in the United States, 2009


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    4th Computational Vaccinology Workshop at ISV
  • Paper of the Month March 2014


    Epidemic of Mumps among Vaccinated Persons, the Netherlands, 2009–2012.

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    4th Computational Vaccinology Workshop at ISV
  • Paper of the Month Febuary 2014


    An Inactivated Enterovirus 71 Vaccine in Healthy Children

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  • Paper of the Month January 2014


    Intramuscular Therapeutic Vaccination Targeting HPV16 Induces T Cell Responses That Localize in Mucosal Lesions.

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  • Paper of the Month December 2013


    Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model

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  • Paper of the Month November 2013


    Immune clearance of highly pathogenic SIV infection

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  • Paper of the Month October 2013


    Microbiome, sex hormones, and immune responses in the reproductive tract: Challenges for vaccine development against sexually transmitted infections.

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  • Paper of the Month September 2013


    Effect of a serogroup A meningococcal conjugate vaccine (PsA-TT) on serogroup A meningococcal meningitis and carriage in Chad: a community trial.

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  • Paper of the Month August 2013


    Epitope engineering and molecular metrics of immunogenicity: A computational approach to VLP-based vaccine design

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  • Paper of the Month July 2013


    A brief history of the global effort to develop a preventive HIV vaccine.

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  • Paper of the Month June 2013


    Intranasal antibody gene transfer in mice and ferrets elicits broad protection against pandemic influenza.

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  • Paper of the Month May 2013


    A Phase I, randomized, open-label study to evaluate the safety and immunogenicity of an enterovirus 71 vaccine.

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  • Paper of the Month Apr 2013


    Boost Interval Matters: A Randomized Phase I Study to Identify the Minimum Interval to Observe the H5DNA Influenza Vaccine Priming Effect.

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  • Paper of the Month Mar 2013


    Safety and Immunogenicity of Heterologous Prime-Boost Immunisation with Plasmodium falciparum Malaria Candidate Vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in Healthy Gambian and Kenyan Adults.

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  • Paper of the Month Feb 2013


    Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis.

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  • Paper of the Month Jan 2013


    DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge.

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  • Paper of the Year 2012


    Immune-correlates analysis of an HIV-1 vaccine efficacy trial.

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  • Paper of the Month Dec 2012

    The safety and effectiveness of self-administrationi of intranasal live attenuated influenza vaccine in adults.
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    Paper of the Month Nov 2012

    Controlling dengue with vaccines in Thailand.
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  • Paper of the Month Sept 2012

    Potential T cell epitopes within swine-origin triple reassortant influenza A (H3N2) variant virus which emerged in 2011:  An immunoinformatics study.
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    Paper of the Month Oct 2012

    A Chimeric Vesiculo/Alphavirus is an Effective Alphavirus Vaccine.
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  • Paper of the Month Jul 2012

    Large intestine-targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection.
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    Paper of the Month Aug 2012

    Vaccination with lipid core peptides fail to induce epitope-specific T cell responses but confers non-specific protective immunity in a malaria model.
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  • Paper of the Month JUN 2012

    Herpes Zoster Vaccine and the Incidence of Recurrent Herpes Zoster in an Immunocompetent Elderly Population...
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    Paper of the Month MAY 2012

    Safety, immunogenicity, and tolerability of meningococcal serogroup B bivalent recombinant lipoprotein 2086 vaccine in healthy adolescents: a randomised ...
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  • Paper of the Month APR 2012

    Cold-Adapted Pandemic 2009 H1N1 Influenza Virus Live Vaccine Elicits Cross- Reactive Immune Responses against Seasonal and H5...

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    Paper of the Month MAR 2012

    Dengue Virus Infection-Enhancing Activity in Serum Samples with Neutralizing Activity as Determined by Using FcγR-Expressing Cells

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  • Paper of the Month FEB 2012

    Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species

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    Paper of the Month JAN 2012

    Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

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  • Paper of the Month DEC 2011

    A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design

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    Paper of the Month NOV 2011

    First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

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  • Paper of the Month OCT 2011

    A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates

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    Paper of the Month SEP 2011

    FDNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials

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  • Paper of the Month AUG 2011

    Vaccine-derived poliomyelitis 12 years after infection in Minnesota

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    Paper of the Month JUL 2011

    Intussusception risk and health benefits of rotavirus vaccination in Mexico and Brazil

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Poll of the Month

Why has there been an overall trend of an increase in reported pertussis cases since the early 1980s?

Points of View March 2015

Commentary from the Journal of the American Medical Association on "Law, Ethics, and Public Health in the Vaccination Debates" - Referenced Article Here

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