Newsletter: Jun 2016

jun 2016 newsletter

Spotlight on ISV Fellows - Connie S. Schmaljohn, Ph.D.

connie s schmaljohnInternational Society for Vaccine Fellow: - Dr. Schmaljohn is a Senior Research Scientist at the United States Army Medical Research Institute of Infectious Diseases (USAMRIID). Dr. Schmaljohn is also an inventor who holds numerous patents protecting inventions involving prophylactic and therapeutic monoclonal antibodies and DNA vaccines. ... read more

Paper of the Month Jun 2016

  • Paper of the Month Feb 2016


    A Recombinant G Protein Plus Cyclosporine A-Based Respiratory Syncytial Virus Vaccine Elicits Humoral and Regulatory T Cell Responses against Infection without Vaccine-Enhanced Disease

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  • Paper of the Month Jan 2016


    Antibody Levels and Protection After Hepatitis B Vaccine: Results of a 30-Year Follow-up Study and Response to a Booster Dose

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  • Paper of the Year 2015


    Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial.

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    2015 2014 2013 2012 2011

  • Paper of the Month DEC 2015


    A new single-dose bivalent vaccine of porcine circovirus type 2 and Mycoplasma hyopneumoniae elicits protective immunity and improves growth performance under field conditions

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    2015 2014 2013 2012 2011

  • Paper of the Month Oct 2015


    Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4+ T cells.

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    20152014 2013 2012 2011

  • Paper of the Month Sep 2015

    Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection AND A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen

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    20152014 2013 2012 2011

  • Paper of the Month May 2015


    Activation of Salmonella Typhi-Specific Regulatory T Cells in Typhoid Disease in a Wild-Type S. Typhi Challenge Model

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  • Paper of the Month APR 2015


    Polysaccharide conjugate vaccine against pneumococcal pneumonia in adults.

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  • Paper of the Month Mar 2015


    Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial

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  • Paper of the Month Feb 2015


    Tapping the Potential of DNA Delivery with Electroporation for Cancer Immunotherapy

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  • Paper of the Month Jan 2015


    The Combination of ISCOMATRIX Adjuvant and TLR Agonists Induces Regression of Established Solid Tumors In Vivo.

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  • Paper of the Month Nov 2014


    Chimpanzee Adenovirus Vector Ebola Vaccine - Preliminary Report.

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  • Paper of the Month Oct 2014


    Prime-Boost Immunization Strategies against Chikungunya Virus.

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  • Paper of the Month September 2014


    TLR5-Mediated Sensing of Gut Microbiota Is Necessary for Antibody Responses to Seasonal InfluenzaVaccination.

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  • Paper of the Month August 2014


    Efficacy of high-dose versus standard-dose influenza vaccine in older adults.

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  • Paper of the Month July 2014


    Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial.

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  • Paper of the Month June 2014


    Early development of broadly neutralizing antibodies in HIV-1–infected infants

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  • Paper of the Month May 2014


    Analysis of HLAA*02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial.

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    4th Computational Vaccinology Workshop at ISV
  • Paper of the Month April 2014


    Economic Evaluation of the Routine Childhood Immunization Program in the United States, 2009


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    4th Computational Vaccinology Workshop at ISV
  • Paper of the Month March 2014


    Epidemic of Mumps among Vaccinated Persons, the Netherlands, 2009–2012.

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    4th Computational Vaccinology Workshop at ISV
  • Paper of the Month Febuary 2014


    An Inactivated Enterovirus 71 Vaccine in Healthy Children

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  • Paper of the Month January 2014


    Intramuscular Therapeutic Vaccination Targeting HPV16 Induces T Cell Responses That Localize in Mucosal Lesions.

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  • Paper of the Month December 2013


    Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model

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  • Paper of the Month November 2013


    Immune clearance of highly pathogenic SIV infection

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  • Paper of the Month October 2013


    Microbiome, sex hormones, and immune responses in the reproductive tract: Challenges for vaccine development against sexually transmitted infections.

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  • Paper of the Month September 2013


    Effect of a serogroup A meningococcal conjugate vaccine (PsA-TT) on serogroup A meningococcal meningitis and carriage in Chad: a community trial.

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  • Paper of the Month August 2013


    Epitope engineering and molecular metrics of immunogenicity: A computational approach to VLP-based vaccine design

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  • Paper of the Month July 2013


    A brief history of the global effort to develop a preventive HIV vaccine.

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  • Paper of the Month June 2013


    Intranasal antibody gene transfer in mice and ferrets elicits broad protection against pandemic influenza.

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  • Paper of the Month May 2013


    A Phase I, randomized, open-label study to evaluate the safety and immunogenicity of an enterovirus 71 vaccine.

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  • Paper of the Month Apr 2013


    Boost Interval Matters: A Randomized Phase I Study to Identify the Minimum Interval to Observe the H5DNA Influenza Vaccine Priming Effect.

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  • Paper of the Month Mar 2013


    Safety and Immunogenicity of Heterologous Prime-Boost Immunisation with Plasmodium falciparum Malaria Candidate Vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in Healthy Gambian and Kenyan Adults.

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  • Paper of the Month Feb 2013


    Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis.

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  • Paper of the Month Jan 2013


    DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge.

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  • Paper of the Year 2012


    Immune-correlates analysis of an HIV-1 vaccine efficacy trial.

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  • Paper of the Month Dec 2012

    The safety and effectiveness of self-administrationi of intranasal live attenuated influenza vaccine in adults.
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    Paper of the Month Nov 2012

    Controlling dengue with vaccines in Thailand.
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  • Paper of the Month Sept 2012

    Potential T cell epitopes within swine-origin triple reassortant influenza A (H3N2) variant virus which emerged in 2011:  An immunoinformatics study.
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    Paper of the Month Oct 2012

    A Chimeric Vesiculo/Alphavirus is an Effective Alphavirus Vaccine.
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  • Paper of the Month Jul 2012

    Large intestine-targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection.
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    Paper of the Month Aug 2012

    Vaccination with lipid core peptides fail to induce epitope-specific T cell responses but confers non-specific protective immunity in a malaria model.
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  • Paper of the Month JUN 2012

    Herpes Zoster Vaccine and the Incidence of Recurrent Herpes Zoster in an Immunocompetent Elderly Population...
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    Paper of the Month MAY 2012

    Safety, immunogenicity, and tolerability of meningococcal serogroup B bivalent recombinant lipoprotein 2086 vaccine in healthy adolescents: a randomised ...
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  • Paper of the Month APR 2012

    Cold-Adapted Pandemic 2009 H1N1 Influenza Virus Live Vaccine Elicits Cross- Reactive Immune Responses against Seasonal and H5...

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    Paper of the Month MAR 2012

    Dengue Virus Infection-Enhancing Activity in Serum Samples with Neutralizing Activity as Determined by Using FcγR-Expressing Cells

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  • Paper of the Month FEB 2012

    Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species

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    Paper of the Month JAN 2012

    Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

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  • Paper of the Month DEC 2011

    A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design

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    Paper of the Month NOV 2011

    First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

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  • Paper of the Month OCT 2011

    A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates

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    Paper of the Month SEP 2011

    FDNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials

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  • Paper of the Month AUG 2011

    Vaccine-derived poliomyelitis 12 years after infection in Minnesota

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    Paper of the Month JUL 2011

    Intussusception risk and health benefits of rotavirus vaccination in Mexico and Brazil

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Points of View Jun 2016

The first Zika-infected, micro encephalic baby was born in the US this week, raising the volume on the Zika debate ... READ MORE


Ana Maria Henao-Restrepo et al. Lancet. 2015. 386:857-866

Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial.

Poll of the Month

There is increasing interest among the scientific community and national funding agencies for research and clinical data to be deposited within database that provide open access platforms for research data sharing.

Does searching of public databases that are designed to share research and clinical data advance your hypothesis-driven research?

Very little if any - 10%
Moderately - 40%
Significantly - 20%
I do not search public database - 30%
The voting for this poll has ended on: 30 Jun 2016 - 00:00

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