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Global Vaccine Congress - Second Conference
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| Sunday December 7, 2008 |
Plenary session 1 - Setting the scene
Chair: Shan Lu |
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Ray Spier |
Welcome |
| 11.00 - 11.10 |
Adel Mahmoud
Princeton University, USA |
Future of Vaccine Discovery |
| 11.45 - 12.10 |
Hiroshi Kiyono
University of Tokyo, Japan |
Development of Self-Administrative Vaccine by MucoRiceTM System |
| 12.10 - 12.35 |
Raymond Welsh
University of Massachusetts Medical School, USA |
Pathogenic epitopes, heterologous immunity, and vaccine design |
| 12.35 - 1.00 |
Mark K. Slifka
Oregon Health & Science University, USA |
Duration of Immunity Following Vaccination: How Long it Can Last and How We Can Make it Better |
| 1.00 - 2.00 |
Lunch |
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Plenary session 2 - Major Infectious Disease Targets
Chair: Shan Lu |
| 2.00 - 2.10 |
Elizabeth Adams
NIAID, USA |
Oral 1 - The Reiterative Discovery Process – HIV Vaccine Prevention Research Moving Forward Post The STEP Trial |
| 2.10 - 2.35 |
Shan Lu
University of Massachusetts Medical School, USA |
Developing HIV Vaccines With Protective Antibody Responses |
| 2.35 - 3.00 |
Adrian Hill
The Jenner Institute, UK |
New Vectored Vaccines for Malaria |
| 3.00 - 3.25 |
Michael J. Brennan
Aeras Global TB Vaccine Foundation, USA |
TB Vaccine Development |
| 3.25 - 4.00 |
Exhibit hall and Coffee |
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| 3.30 - 4.00 |
Poster Session |
Human Vaccines Infectious Disease
Human Vaccines Non Infectious Disease |
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Plenary session 3 - Non-traditional vaccines
Chair: Rino Rappouli |
| 4.00 - 4.25 |
Annie de Groot
EpiVax Inc., USA |
Computer-driven Vaccine Design: From Concept to Reality |
| 4.25 – 4.50 |
Polly Gregor
Memorial Sloan-Kettering Cancer Center, USA |
Of Mice and Men (and Dogs): Clinical Development of Xenogeneic DNA Vaccines for Cancer. |
| 4.50 - 5.00 |
Eric Huang
University of California USA |
Oral 2 - Acne Vaccines Targeting P. acnes Virulent Factors |
| 5.00 - 5.10 |
Marcus Hoerer
MediGene AG, Germany |
Oral 3 - Development of AAV as Potent B-cell Vaccine Directed Against Human IgE for the Treatment of Severe Allergic Asthma |
| 5.10 - 5.20 |
William Decker
University of Texas MD Anderson Cancer Centre, USA |
Oral 4 - Th-1 Immunity is Regulated by Dendritic Cell Comparison of MHC Class I and Class II Antigens: Implications for Successful Immunotherapy of Neoplasia |
| 5.20 - 5.30 |
Philippe Leff
National Institute of Psychiatry, Mexico |
Oral 5 - Preclinical Studies On The Generation of Conjugated Vaccines for Addictive Drugs |
| 5.30 - 7.30 |
Opening reception - Poster & Exhibit hall |
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| Monday December 8, 2008 |
Plenary sessions 4 – Adjuvants
Chair: Hiroshi Kiyono |
| 8.30 - 8.55 |
Kate A. Fitzgerald
University of Massachusetts Medical School, USA |
Pattern Recognition Receptors and the Adjuvant Response |
| 8.55 - 9.20 |
Dennis Klinman
NCI-Frederick, USA |
Use of CpG Oligonucleotides as a Vaccine Adjuvant |
| 9.20 - 9.30 |
Angelika Banzhoff
Novartis, Germany |
Oral 6 - An MF-59 Adjuvanted H5N1 Clade 1 Pre-pandemic Vaccine Confers Cross-reactive Antibodies to a Clade 2 H5N1 Virus Strain |
| 9.30 - 9.40 |
Stephane Heijmans
ResearchLink, Belgium |
Oral 7 - AS03-Adjuvanted Prepandemic Influenza Vaccine: High Immunogenicity In The Elderly |
| 9.40 - 9.50 |
Stephanie Eisenbarth
Yale School of Medicine, USA |
Oral 8 - Aluminum Hydroxide Adjuvants Activate the Immune System Through the Nalp3 Inflammasome |
| 9.50 - 10.00 |
Eric Tartour
Hopital Européen Georges Pompidou, France |
Oral 9 - The Non Toxic B Subunit of Shiga Toxin Coupled to Various Antigens Elicits Mucosal Humoral and Cellular Immune Responses. |
| 10.00 - 10.10 |
Marcin Kwissa
Emory Vaccine Center, USA |
Oral 10 - Adjuvanting a DNA Vaccine With a TLR9 Ligand Plus Flt3 Ligand Results in Enhanced Cellular Immunity Against the Simian Immunodeficiency Virus |
| 10.10 - 10.20 |
Bin Wang
China Agricultural University, China |
Oral 11 - Activation of MyD88 Dependent TLR 7/8 Pathway Leads to Cell Mediated Responses by Levamisole As A Potent Adjuvant for Therapeutic Vaccination Against HBV Infection |
| 10.20 - 10.30 |
Wei Li
University of Massachusetts Medical School, USA |
Oral 12 - DNA Vaccine Prime Improved the Antigen-specific B Cell Memory and Longevity of B Cell Responses Against V Antigen of Yersinia Pestis in Mice |
| 10.30 - 11.00 |
Exhibit hall and Coffee |
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| 10.30 - 11.00 |
Poster Session |
Adjuvants
Delivery Systems
Late Breaker
Production & Other |
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Plenary sessions 5 - Delivery systems
Chair: Peter Nara |
| 11.00 - 11.25 |
Bruce G. Weniger
Centers for Disease Control and Prevention, USA |
Vaccination Into or Onto the Skin: Advantages, Accomplishments, Actualizations, and Adumbrations of the Cutaneous Route |
| 11.25 - 11.50 |
Dan Barouch
Harvard Medical School, USA |
Novel Adenovirus Vector-Based Vaccines for HIV-1 |
| 11.50 - 12.00 |
Julia Hurwitz
St. Jude Children's Research Hospital USA |
Oral 13 - Development of Sendai Virus-based Vaccines to Prevent Pediatric Respiratory Virus Infections |
| 12.00 - 12.10 |
Tina Villar
Intercell USA Inc |
Oral 14 - Field Efficacy Results From a Field Trial Show a Patch Containing Heat Labile Enterotoxin from Escherichia coli (LT) Protects Against Travelers’ Diarrhea |
| 12.10 - 12.20 |
David Chang, University of Queensland, Australia |
Oral 15 - West Nile virus DNA Vaccine Producing Single Round Infectious Particles Protects Mice From Lethal Encephalitis and Induce Virus-neutralising Antibodies in Horses |
| 12.20 - 12.30 |
Brian Livinston, Ichor Medical Systems, USA |
Oral 16 - Electroporation Mediated DNA Immunization: Comparative Performance Versus Classical Vaccine Approaches and Transition to Human Clinical Testing |
| 12.30 - 2.15 |
Lunch |
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| 12.30 - 1.30 |
Poster Session |
Adjuvants
Delivery Systems
Late Breaker
Production
Other |
| 1.30 - 2.00 |
ISV Business Meeting Harbor Ballroom |
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Plenary sessions 6 - ISV President presentation
Chair: Ray Spier |
| 2.15 - 3.15 |
Gregory A. Poland
Mayo Vaccine Research Group, USA |
Influenza Immunization of Health Care Workers: A Patient Safety Imperative |
| ISV selected abstract presentation |
| 3.15 - 3.25 |
Jan Pravsgaard Christensen
University of Copenhagen, Denmark |
Oral 17 - Improved immunogenicity of Adenoviral Vaccines: Impact of Tethering the Vaccine Antigen to MHC-class II Associated Invariant Chain |
| 3.25 - 3.35 |
Indresh Srivastava
Novartis Vaccines, USA |
Oral 18 - Toward the Development of a SARS Vaccine |
| 3.35 - 3.45 |
Mart Ustav
FIT Biotech Oy Eesti AS, Estonia |
Oral 19 - Development of the DNA Plasmid Based Genetic Vaccine Vectors, Which Use Segregation/Partitioning Functions of the Episomally Replicating DNA Viruses. |
| 3.45 - 3.55 |
Vidya Arankalle (absent)
National Institute for Virology, India |
Oral 20 - Development of recombinant G protein-based vaccine for Chandipura virus |
| 3.55 - 4.30 |
Exhibit hall and Coffee |
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| 4.00 - 4.30 |
Poster Session |
Adjuvants, Delivery Systems
Late Breaker
Production
Other |
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Breakout session 1 - Vaccine production and clinical use
Harbor Ballroom 2 & 3
Chair: Bruce Weniger |
| 4.30 - 4.55 |
Rich Costantino
USA |
Stability of Vaccines |
| 4.55 - 5.05 |
Stephan Zweig
Clinisense Corporation, USA |
Oral 21 - Vaccine Stability Monitoring Using the LifeTrack® Electronic Stability Monitor |
| 5.05 - 5.15 |
Derek Gregg
Vandalia Research, USA |
Oral 22 - System and Process for Large-Scale DNA Vaccine Production by PCR |
| 5.15 - 5.25 |
Denis Leclerc
Laval University, Canada |
Oral 23 - Development of an Universal Influenza A Vaccine Using an Innovative Plant Virus Based Platform |
| 5.25 - 5.35 |
Hana El Sahly, Baylor College of Medicine, USA |
Oral 24 - Phase 1, Double-Blinded, Placebo-Controlled, Dosage-Escalation Study of the Safety and Immunogenicity of EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly |
| 5.35 - 5.45 |
Derek Brown
RTI International Research, USA |
Oral 25 - Mother and Daughter Preferences and Willingness to Pay for HPV Vaccination |
| 5.45 - 5.55 |
Mark Steinhoff
Cincinnati Childrens Hospital Medical Center, USA |
Oral 26 - Maternal Immunization: an Underutilized Strategy to Protect both Mothers and Infants |
| 5.55 - 6.05 |
Cathy Panozzo
Center for Disease Control and Prevention, USA |
Oral 27 - Delayed Onset and Diminished Magnitude of Rotavirus Activity--United States, November 2007-May 2008 |
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Breakout session 2 - Late Breakers Abstracts – 1
Harbor Ballroom 1
Chair: Bob Chen |
| 4.30 - 4.40 |
Jan ter Meulen
Merck & Co, USA |
Oral 28 - Modeling of a Highly Conserved Influenza HA2 Epitope for Vaccination and Evaluation in the Mouse Challenge Model. |
| 4.40 - 4.50 |
Myra Widjojoatmodjo
Netherlands Vaccine Institute, The Netherlands |
Oral 29 - A highly Attenuated Recombinant Human Respiratory Syncytial Virus Lacking the G Protein Confers Long Time Protection Against RSV Infection in Cotton Rats. |
| 4.50 - 5.00 |
Maryann Giel-Moloney
Acambis, USA |
Oral 30 - RepliVax®: New Replication-Defective Flavivirus Vaccines and Vectors for Non-Flavivirus Immunogens |
| 5.00 - 5.10 |
De-Chu Tang
Vaxin Inc, USA |
Oral 31 - Non-replicating Adenovirus-Vectored Avian Influenza Vaccine as a Rapid-Response Tool for Mitigating a Pandemic |
| 5.10 - 5.20 |
Eryu Wang
University of Texas, USA |
Oral 32 - Chimeric Alphavirus Vaccines for Western Equine Encephalitis |
| 5.20 - 5.30 |
Dorothee Herlyn
The Wistar Institute, USA |
Oral 33 - Antigens Recognized by Cytotoxic and Helper T Lymphocytes with Vaccine Potential for Cancer Patients |
| 5.30 - 5.40 |
Peter Rottier
Utrecht University, The Netherlands |
Oral 34 - A Genetically Attenuated Feline Coronavirus Vaccine: Protection Against Feline Infectious Peritonitis (FIP) by Cellular Rather Than by Virus-Neutralizing Immunity |
| 5.40 - 5.50 |
Aalzen De Haan
The Netherlands |
Oral 35 - Fusion Inactivation of H5N1 Whole Inactivated Virus (WIV) Vaccine Does Not Compromise its Superior Immunogenicity. |
| 5.50 - 6.00 |
Cristina Nazarov
Uniformed Services University, USA |
Oral 36 - Down-Regulation of Influenza Viral Vaccination by CD4+25hi T-Regulatory Cells |
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| Coaches depart from D St. entrance of the Westin Waterfront (concourse level) at 7.00pm |
| Tuesday December 9, 2008 |
Plenary session 7 - Novel Bacterial Vaccines
Chair: Jan ter Meulen |
| 8.30 - 8.55 |
Rino Rappuoli
Novartis Vaccines and Diagnostics, Italy |
Vaccines: An Health Insurance of the 21st century |
| 8.55 - 9.20 |
John W. Shiver
Merck and Co Inc., USA |
Development of a Novel Staphylococcus Aureus Vaccine Based on a Conserved Protein Antigen |
| 9.20 - 9.45 |
Jennifer Schranz
Wyeth, USA |
Pneumococcal Conjugate Vaccines: What Do We Know and What Do We Need? |
| 9.45 - 9.55 |
Carmen Giefing
Intercell AG, Austria |
Oral 37 - Development of a Full Coverage Pneumococcal Vaccine Comprising Highly Conserved Proteins With a Crucial Function in the Bacterial Life Cycle |
| 9.55 - 10.05 |
Peter Dull
Novartis, USA |
Oral 38 - A Phase III Head-to-Head Comparison of a Novel Quadrivalent Meningococcal Conjugate Vaccine, MenACWY-CRM, With the Licensed Meningococcal ACWY Conjugate Vaccine, Menactra®, in Healthy Subjects 11-55 Years of Age |
| 10.05 - 10.15 |
Yongqun He
University of Michigan, USA |
Oral 39 - Vaxign: a Web-based Vaccine Target Design Program for Reverse Vaccinology |
| 10:15-10:25 |
Daniel Scott
Wyeth, USA |
Oral 40 - Safety & Immunologic Non-inferiority of 13-valent Pneumococcal Conjugate Vaccine Compared to 7-valent Pneumococcal Conjugate Vaccine Given with Routine Vaccines in Healthy Infants |
| 10.25 - 11.00 |
Exhibit hall and Coffee |
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| 10.30 - 11.00 |
Poster session |
Veterinary Vaccines
Immunology/Animal Models |
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Plenary session 8 - Emerging Infectious Disease & Biodefense
Harbor Ballroom 2 & 3
Chair: John Oxford & Alan Barrett |
| 11.00 - 11.25 |
Alan Barrett
University of Texas Medical Branch, USA |
Characterization of Type-specific and Dengue Complex Antigenic Sites on the Envelope Protein Domain III of Dengue Viruses |
| 11.25 - 11.50 |
John S. Oxford
Retroscreen Virology Ltd, UK |
The Ferret and Human Models for Influenza Vaccine Evaluation |
| 11.50 - 12.00 |
Trudy Morrison
University of Massachusetts Medical School, USA |
Oral 41 - The Immunogenicity and Efficacy of a Virus-like Particle Vaccine Candidate against Respiratory Syncytial Virus in Mice |
| 12.00 - 12.10 |
Nicolas Sabarth, Baxter Innovations GmbH, Austria |
Oral 42 - Induction of Longitudinal Cross-Clade Anti-H5N1 Immunity and Protection by Homologous and Heterologous Prime-Boost Immunization Regimes with Whole Virus H5N1 Influenza Candidate vaccines |
| 12.10 - 12.20 |
George Bettinger
University of Texas Medical Branch, USA |
Oral 43 - Genetic and Clinical Evaluation of MP-12: a live Attenuated Vaccine for Rift Valley Fever Virus (RVFV) |
| 12.20 - 12.30 |
Igor Lukashevich
Institute of Human Virology, USA |
Oral 44 - A ML29 Reassortant Lassa Fever Vaccine is Safe and Induces Broad Cell-Mediated Protective Immune Responses in Experimental Animals |
| 12.30 - 12.40 |
Hana El Sahly
Baylor College of Medicine, USA |
Oral 45 - Phase 1, Double-Blinded, Placebo-Controlled Dose-Escalation Study of the Safety and Reactogenicity of Francisella tularensis Live Vaccine Strain (LVS) Administered by the Scarification or Subcutaneous Route |
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Breakout session 3 - Late Breaker Abstracts – 2
Harbor Ballroom 1
Chair: John Shiver |
| 11.00 - 11.10 |
Harry Hull
HF Hull & Associates, USA |
Oral 46 - Strategies for Achieving Efficient Implementation of an Expanded ACIP Recommendation for Influenza Vaccination of School-aged Children |
| 11.10 - 11.20 |
Benoit Dervaux
CRESGE, France |
Oral 47 - The value of Information When Considering Introduction of a New Vaccine in the Immunisation Schedule: A Conjoint Analysis Conducted in Europe |
| 11.20 - 11.30 |
David Klatzmann (absent)
UMR 7087 UPMC-CNRS, France |
Oral 48 - Rational Design and Standardized Evaluation of Novel Genetic Vaccines |
| 11.30 - 11.40 |
Mauro Pistello
University of Pisa, Italy |
Oral 49 - Prime-Boost Vaccination with DNA-Transduced Autologous Lymphocytes Protects Against Fully Virulent Homologous Challenge in the Feline Immunodeficiency Virus AIDS Model |
| 11.40 - 11.50 |
Tomonori Nochi
University of Tokyo, Japan |
Oral 50 - Exploit of Nanogel as a Novel Carrier of Mucosal Vaccine: Nanogel Mucosal Vaccine Effectively Induces Protective Immunity Against Botulinum Toxin |
| 11.50 - 12.00 |
Wil Landman
Animal Health Service, The Netherlands |
Oral 51 - Vaccination of Broiler Chickens with Dry Powder Vaccines as an Alternative for Liquid Spray and Aerosol Vaccination |
| 12.00 - 12.10 |
Dominique Schols
Rega Institute for Medical Research, Belgium |
Oral 52 - HIV-1 Resistance Towards CADA-induced CD4 Receptor-Targeted Inhibition is Associated with Increased Sensitivity to Neutralizing Antibodies. |
| 12.10 - 12.20 |
Valentina Feodorova
Saratov State University, Russia |
Oral 53 - Yersinia pestis Live Vaccine with Improved Characteristics |
| 12.20 - 12.30 |
Julie Milstien
University of Maryland School of Medicine, USA |
Oral 54 - Challenges and Potential Solutions to Innovative Vaccine Development in Developing Countries |
| 12.30 - 2.00 |
Exhibit hall and Lunch |
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| 12.45 - 1.15 |
Poster session |
Veterinary Vaccines
Immunology/Animal Models |
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Plenary 9 - Vaccine Policy and public health issues
Chair: Ray Spier |
| 2.00 -2.25 |
Dack Dalrymple
Dalrymple & Associates, LLC, USA |
Current & Future U.S. Government Funding for Vaccine R&D and Acquisition |
| 2.25 - 2.50 |
Bob Chen
Centers for Disease Control and Prevention, USA |
Enhancing Vaccine Safety Assessment During Vaccine Development: Some Modest Proposals |
2.50 - 3.15 |
Jon Andrus
Pan American Health Organization, USA |
Implementing Vaccination Programs in Developing Countries |
| 3.15 - 3.40 |
Peter Nara
Biological Mimetics Inc, USA |
Improving on Mother Nature's Immunogenicity |
| 3.40 - 4.05 |
Ray Spier |
Dealing with Ethical Issues in the Area of Vaccines and Vaccination |
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| Ray Spier and Shan Lu |
Closing Summary |
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